Transcription Driven Somatic DNA Methylation within the Imprinted Gnas Cluster

Transcription Driven Somatic DNA Methylation within the Imprinted Gnas Cluster

Differential marking of genes in female and male gametes by DNA methylation is essential to genomic imprinting. In female gametes transcription traversing differentially methylated regions (DMRs) is a common requirement for de novo methylation at DMRs. At the imprinted Gnas cluster oocyte specific t...

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Bibliographic Details
Main Authors: Mehta, Stuti, Williamson, Christine M., Ball, Simon, Tibbit, Charlotte, Beechey, Colin, Fray, Martin, Peters, Jo
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319783/

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