Uncoupling Antisense-Mediated Silencing and DNA Methylation in the Imprinted Gnas Cluster

Uncoupling Antisense-Mediated Silencing and DNA Methylation in the Imprinted Gnas Cluster

There is increasing evidence that non-coding macroRNAs are major elements for silencing imprinted genes, but their mechanism of action is poorly understood. Within the imprinted Gnas cluster on mouse chromosome 2, Nespas is a paternally expressed macroRNA that arises from an imprinting control regio...

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Bibliographic Details
Main Authors: Williamson, Christine M., Ball, Simon T., Dawson, Claire, Mehta, Stuti, Beechey, Colin V., Fray, Martin, Teboul, Lydia, Dear, T. Neil, Kelsey, Gavin, Peters, Jo
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063750/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063750/

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