An evolutionary arms race between KRAB zinc finger genes 91/93 and SVA/L1 retrotransposons

Throughout evolution, primate genomes have been modified by waves of retrotransposon insertions1,2,3. For each wave, the host eventually finds a way to repress retrotransposon transcription and prevent further insertions. In mouse embryonic stem cells (mESCs), transcriptional silencing of retrotrans...

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Bibliographic Details
Main Authors: Jacobs, Frank MJ, Greenberg, David, Nguyen, Ngan, Haeussler, Maximilian, Ewing, Adam D, Katzman, Sol, Paten, Benedict, Salama, Sofie R, Haussler, David
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268317/