KRAB-containing zinc-finger repressor proteins
The largest family of zinc-finger transcription factors comprises those containing the Krüppel-associated box (or KRAB domain). The KRAB domain behaves as a transcriptional repressor domain and the C2H2 zinc-finger motifs bind DNA. Members of the family are involved in maintenance of the nucleolus,...
Main Author: | |
---|---|
Format: | Online |
Language: | English |
Published: |
BioMed Central
2003
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC328446/ |