KRAB-containing zinc-finger repressor proteins

The largest family of zinc-finger transcription factors comprises those containing the Krüppel-associated box (or KRAB domain). The KRAB domain behaves as a transcriptional repressor domain and the C2H2 zinc-finger motifs bind DNA. Members of the family are involved in maintenance of the nucleolus,...

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Bibliographic Details
Main Author: Urrutia, Raul
Format: Online
Language:English
Published: BioMed Central 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC328446/