STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion

STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion

Calcium signaling mediated by STIM1 and Orai1 activates Src to promote invadopodium assembly while simultaneously promoting MT1-MMP recycling to the plasma membrane to promote ECM degradation.

Bibliographic Details
Main Authors: Sun, Jianwei, Lu, Fujian, He, Huifang, Shen, Junling, Messina, Jane, Mathew, Rahel, Wang, Dapeng, Sarnaik, Amod A., Chang, Wei-Chiao, Kim, Minjung, Cheng, Heping, Yang, Shengyu
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242838/
id pubmed-4242838
recordtype oai_dc
spelling pubmed-42428382015-05-24 STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion Sun, Jianwei Lu, Fujian He, Huifang Shen, Junling Messina, Jane Mathew, Rahel Wang, Dapeng Sarnaik, Amod A. Chang, Wei-Chiao Kim, Minjung Cheng, Heping Yang, Shengyu Research Articles Calcium signaling mediated by STIM1 and Orai1 activates Src to promote invadopodium assembly while simultaneously promoting MT1-MMP recycling to the plasma membrane to promote ECM degradation. The Rockefeller University Press 2014-11-24 /pmc/articles/PMC4242838/ /pubmed/25404747 http://dx.doi.org/10.1083/jcb.201407082 Text en © 2014 Sun et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Sun, Jianwei
Lu, Fujian
He, Huifang
Shen, Junling
Messina, Jane
Mathew, Rahel
Wang, Dapeng
Sarnaik, Amod A.
Chang, Wei-Chiao
Kim, Minjung
Cheng, Heping
Yang, Shengyu
spellingShingle Sun, Jianwei
Lu, Fujian
He, Huifang
Shen, Junling
Messina, Jane
Mathew, Rahel
Wang, Dapeng
Sarnaik, Amod A.
Chang, Wei-Chiao
Kim, Minjung
Cheng, Heping
Yang, Shengyu
STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
author_facet Sun, Jianwei
Lu, Fujian
He, Huifang
Shen, Junling
Messina, Jane
Mathew, Rahel
Wang, Dapeng
Sarnaik, Amod A.
Chang, Wei-Chiao
Kim, Minjung
Cheng, Heping
Yang, Shengyu
author_sort Sun, Jianwei
title STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
title_short STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
title_full STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
title_fullStr STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
title_full_unstemmed STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
title_sort stim1- and orai1-mediated ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
description Calcium signaling mediated by STIM1 and Orai1 activates Src to promote invadopodium assembly while simultaneously promoting MT1-MMP recycling to the plasma membrane to promote ECM degradation.
publisher The Rockefeller University Press
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242838/
_version_ 1613160363474288640

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