STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion

STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion

Calcium signaling mediated by STIM1 and Orai1 activates Src to promote invadopodium assembly while simultaneously promoting MT1-MMP recycling to the plasma membrane to promote ECM degradation.

Bibliographic Details
Main Authors: Sun, Jianwei, Lu, Fujian, He, Huifang, Shen, Junling, Messina, Jane, Mathew, Rahel, Wang, Dapeng, Sarnaik, Amod A., Chang, Wei-Chiao, Kim, Minjung, Cheng, Heping, Yang, Shengyu
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242838/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242838/

Similar Items