Orais and STIMs: physiological mechanisms and disease
The stromal interaction molecules STIM1 and STIM2 are Ca2+ sensors, mostly located in the endoplasmic reticulum, that detect changes in the intraluminal Ca2+ concentration and communicate this information to plasma membrane store-operated channels, including members of the Orai family, thus mediatin...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Blackwell Publishing Ltd
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822919/ |