Life without tRNAIle-lysidine synthetase: translation of the isoleucine codon AUA in Bacillus subtilis lacking the canonical tRNA2Ile
Translation of the isoleucine codon AUA in most prokaryotes requires a modified C (lysidine or agmatidine) at the wobble position of tRNA2Ile to base pair specifically with the A of the AUA codon but not with the G of AUG. Recently, a Bacillus subtilis strain was isolated in which the essential gene...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919564/ |