Double-focusing mixing jet for XFEL study of chemical kinetics

A novel method for time-resolved study of chemical kinetics using a windowless mixing jet at an X-ray free-electron laser (XFEL) is described and demonstrated. The short mixing time gives a time resolution of about 250 µs; the design introduces controllable delays after the initiation of a chemical...

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Bibliographic Details
Main Authors: Wang, Dingjie, Weierstall, Uwe, Pollack, Lois, Spence, John
Format: Online
Language:English
Published: International Union of Crystallography 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211133/
Description
Summary:A novel method for time-resolved study of chemical kinetics using a windowless mixing jet at an X-ray free-electron laser (XFEL) is described and demonstrated. The short mixing time gives a time resolution of about 250 µs; the design introduces controllable delays after the initiation of a chemical reaction, allowing the possibility for detection of transient structures by an XFEL beam pulse. Applications may include time-resolved enzyme–substrate imaging or protein folding.