Structure and function of cohesin’s Scc3/SA regulatory subunit
•Crystal structure of cohesin subunit Scc3/SA, showing irregular HEAT-like repeats.•Scc3 C-terminal domain binds Scc1, cohesin’s kleisin.•Scc1’s Scc3 binding region mapped.•Scc3 turns over in G2/M while maintaining cohesin’s association with chromosomes.•Scc3 promotes de-acetylation of Smc3 upon Scc...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Science B.V
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175184/ |