Identification and Characterization of Sa/Scc3p Subunits in the Xenopus and Human Cohesin Complexes

A multisubunit protein complex, termed cohesin, plays an essential role in sister chromatid cohesion in yeast and in Xenopus laevis cell-free extracts. We report here that two distinct cohesin complexes exist in Xenopus egg extracts. A 14S complex (x-cohesinSA1) contains XSMC1, XSMC3, XRAD21, and a...

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Bibliographic Details
Main Authors: Losada, Ana, Yokochi, Tomoki, Kobayashi, Ryuji, Hirano, Tatsuya
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175199/