Cohesin’s DNA Exit Gate Is Distinct from Its Entrance Gate and Is Regulated by Acetylation
Sister chromatid cohesion is mediated by entrapment of sister DNAs by a tripartite ring composed of cohesin’s Smc1, Smc3, and α-kleisin subunits. Cohesion requires acetylation of Smc3 by Eco1, whose role is to counteract an inhibitory (antiestablishment) activity associated with cohesin’s Wapl subun...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Cell Press
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485559/ |