Preferential Effect of Akt2-Dependent Signaling on the Cellular Viability of Ovarian Cancer Cells in Response to EGF
Objective: Overexpression of the epidermal growth factor receptor (EGFR) is associated with the malignant phenotype in many cancers including ovarian cancer, which leads to increased cell proliferation and survival. In spite of emerging EGFR inhibitors as a potentially useful agent, they are largely...
Main Authors: | Khabele, Dineo, Kabir, Syeda M, Dong, Yuanlin, Lee, Eunsook, Rice, Valerie Montgomery, Son, Deok-Soo |
---|---|
Format: | Online |
Language: | English |
Published: |
Ivyspring International Publisher
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174511/ |
Similar Items
-
Aspirin Blocks EGF-stimulated Cell Viability in a COX-1 Dependent Manner in Ovarian Cancer Cells
by: Cho, May, et al.
Published: (2013) -
Characteristics of chemokine signatures elicited by EGF and TNF in ovarian cancer cells
by: Son, Deok-Soo, et al.
Published: (2013) -
The Therapeutic Potential of Class I Selective Histone Deacetylase Inhibitors in Ovarian Cancer
by: Khabele, Dineo
Published: (2014) -
Heated Intraperitoneal Chemotherapy in the Management of Advanced Ovarian Cancer
by: Andrea Jewell, et al.
Published: (2018-09-01) -
CXCR2-Driven Ovarian Cancer Progression Involves Upregulation of Proinflammatory Chemokines by Potentiating NF-κB Activation via EGFR-Transactivated Akt Signaling
by: Dong, Yuan-Lin, et al.
Published: (2013)