Preferential Effect of Akt2-Dependent Signaling on the Cellular Viability of Ovarian Cancer Cells in Response to EGF
Objective: Overexpression of the epidermal growth factor receptor (EGFR) is associated with the malignant phenotype in many cancers including ovarian cancer, which leads to increased cell proliferation and survival. In spite of emerging EGFR inhibitors as a potentially useful agent, they are largely...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Ivyspring International Publisher
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174511/ |