HBx Inhibits CYP2E1 Gene Expression via Downregulating HNF4α in Human Hepatoma Cells

HBx Inhibits CYP2E1 Gene Expression via Downregulating HNF4α in Human Hepatoma Cells

CYP2E1, one of the cytochrome P450 mixed-function oxidases located predominantly in liver, plays a key role in metabolism of xenobiotics including ethanol and procarcinogens. Recently, down-expression of CYP2E1 was found in hepatocellular carcinoma (HCC) with the majority to be chronic hepatitis B v...

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Bibliographic Details
Main Authors:	Liu, Hongming, Lou, Guiyu, Li, Chongyi, Wang, Xiaodong, Cederbaum, Arthur I., Gan, Lixia, Xie, Bin
Format:	Online
Language:	English
Published:	Public Library of Science 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169590/

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