SUMOylation of HNF4α regulates protein stability and hepatocyte function

The coordination of signalling pathways within the cell is vital for normal human development and post-natal tissue homeostasis. Gene expression and function is therefore tightly controlled at a number of levels. We investigated the role that post-translational modifications play during human hepato...

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Bibliographic Details
Main Authors: Zhou, Wenli, Hannoun, Zara, Jaffray, Ellis, Medine, Claire N., Black, James R., Greenhough, Sebastian, Zhu, Liang, Ross, James A., Forbes, Stuart, Wilmut, Ian, Iredale, John P., Hay, Ronald T., Hay, David C.
Format: Online
Language:English
Published: The Company of Biologists 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445325/