Syntheses of 15N-labeled pre-queuosine nucleobase derivatives
Pre-queuosine or queuine (preQ1) is a guanine derivative that is involved in the biosynthetic pathway of the hypermodified tRNA nucleoside queuosine (Que). The core structure of preQ1 is represented by 7-(aminomethyl)-7-deazaguanine (preQ1 base). Here, we report the synthesis of three preQ1 base der...
Main Authors: | Levic, Jasmin, Micura, Ronald |
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Format: | Online |
Language: | English |
Published: |
Beilstein-Institut
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168690/ |
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