Enzymatic synthesis of nucleobase-modified UDP-sugars: scope and limitations

Enzymatic synthesis of nucleobase-modified UDP-sugars: scope and limitations

•Enzymatic conversion of 5-aryl-substituted UTP to UDP-galactose derivatives.•UDP-glucose pyrophosphorylase was particularly effective.•Epimerization of 5-substituted UDP-glucoses with Erwinia UDP-glucose 4″-epimerase.

Bibliographic Details
Main Authors: Wagstaff, Ben A., Rejzek, Martin, Pesnot, Thomas, Tedaldi, Lauren M., Caputi, Lorenzo, O’Neill, Ellis C., Benini, Stefano, Wagner, Gerd K., Field, Robert A.
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340641/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340641/

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