PIDD mediates and stabilizes the interaction between RAIDD and Caspase-2 for the PIDDosome assembly
The PIDDosome, which is an oligomeric signaling complex composed of PIDD, RAIDD and caspase-2, can induce proximity-based dimerization and activation of caspase-2. In the PIDDosome assembly, the adaptor protein RAIDD interacts with PIDD and caspase-2 via CARD:CARD and DD:DD, respectively. To analyze...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Society for Biochemistry and Molecular Biology
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133880/ |