PIDDosome Expression and the Role of Caspase-2 Activation for Chemotherapy-Induced Apoptosis in RCCs

Background: The importance of caspase-2 activation for mediating apoptosis in cancer is not clear and seems to differ between different tumour types. Furthermore, only few data have been obtained concerning the expression of caspase-2, which can be alternatively spliced into caspase-2L and caspase-...

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Bibliographic Details
Main Authors: Heikaus, Sebastian, Pejin, Igor, Gabbert, Helmut Erich, Ramp, Uwe, Mahotka, Csaba
Format: Online
Language:English
Published: IOS Press 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619288/