Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle
Patterning of the vertebrate optic vesicle into proximal/optic stalk and distal/neural retina involves midline-derived Hedgehog (Hh) signalling, which promotes stalk specification. In the absence of Hh signalling, the stalks are not specified, causing cyclopia. Recent studies showed that the cell ad...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Pub. Group
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102123/ |