Sonic Hedgehog Promotes Tumor Cell Survival by Inhibiting CDON Pro-Apoptotic Activity

Sonic Hedgehog Promotes Tumor Cell Survival by Inhibiting CDON Pro-Apoptotic Activity

CDON is a novel Sonic Hedgehog (SHH) dependence receptor and targeting the SHH-CDON interaction could represent an alternative therapeutic strategy for patients suffering from tumors that express high SHH levels.

Bibliographic Details
Main Authors: Delloye-Bourgeois, Céline, Gibert, Benjamin, Rama, Nicolas, Delcros, Jean-Guy, Gadot, Nicolas, Scoazec, Jean-Yves, Krauss, Robert, Bernet, Agnès, Mehlen, Patrick
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735457/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735457/

Similar Items