Modelling Proteasome and Proteasome Regulator Activities

Proteasomes are key proteases involved in a variety of processes ranging from the clearance of damaged proteins to the presentation of antigens to CD8+ T-lymphocytes. Which cleavage sites are used within the target proteins and how fast these proteins are degraded have a profound impact on immune sy...

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Bibliographic Details
Main Authors: Liepe, Juliane, Holzhütter, Herman-Georg, Kloetzel, Peter M., Stumpf, Michael P. H., Mishto, Michele
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101499/