T lymphocytes export proteasomes by way of microparticles: a possible mechanism for generation of extracellular proteasomes

The 20S proteasome is almost exclusively localized within cells. High levels of extracellular proteasomes are also found circulating in the blood plasma of patients suffering from a variety of inflammatory, autoimmune and neoplastic diseases. However, the origin of these proteasomes remained enigmat...

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Bibliographic Details
Main Authors: Bochmann, Isabel, Ebstein, Frédéric, Lehmann, Andrea, Wohlschlaeger, Jeremias, Sixt, Stephan Urs, Kloetzel, Peter-Michael, Dahlmann, Burkhardt
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916118/