The tumor suppressor p53 connects ribosome biogenesis to cell cycle control: a double-edged sword
Since its first description more than 30 years ago p53 has become a paradigm for a protein with versatile functions. P53 sensitizes a large variety of genetic alterations and has been entitled the guardian of the genome. Stabilization of p53 upon DNA damage is accompanied by a complex pattern of mod...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Impact Journals LLC
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053546/ |