The tumor suppressor p53 connects ribosome biogenesis to cell cycle control: a double-edged sword
Since its first description more than 30 years ago p53 has become a paradigm for a protein with versatile functions. P53 sensitizes a large variety of genetic alterations and has been entitled the guardian of the genome. Stabilization of p53 upon DNA damage is accompanied by a complex pattern of mod...
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Bibliographic Details
Main Authors: |
Hölzel, Michael,
Burger, Kaspar,
Mühl, Bastian,
Orban, Mathias,
Kellner, Markus,
Eick, Dirk |
Format: | Online
|
Language: | English |
Published: |
Impact Journals LLC
2010
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053546/
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