Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+

Assessment of the network of toxicity pathways by Omics technologies and bioinformatic data processing paves the road toward a new toxicology for the twenty-first century. Especially, the upstream network of responses, taking place in toxicant-treated cells before a point of no return is reached, is...

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Bibliographic Details
Main Authors: Krug, A K, Gutbier, S, Zhao, L, Pöltl, D, Kullmann, C, Ivanova, V, Förster, S, Jagtap, S, Meiser, J, Leparc, G, Schildknecht, S, Adam, M, Hiller, K, Farhan, H, Brunner, T, Hartung, T, Sachinidis, A, Leist, M
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047858/