Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells

Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells

Human embryonic stem cells (hESCs) may be applied to develop human-relevant sensitive in vitro test systems for monitoring developmental toxicants. The aim of this study was to identify potential developmental toxicity mechanisms of the histone deacetylase inhibitors (HDAC) valproic acid (VPA), sube...

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Bibliographic Details
Main Authors: Meganathan, K, Jagtap, S, Srinivasan, S P, Wagh, V, Hescheler, J, Hengstler, J, Leist, M, Sachinidis, A
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669700/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669700/

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