The DNA Double-Strand Break Response Is Abnormal in Myeloblasts From Patients With Therapy-Related Acute Myeloid Leukemia
The complex chromosomal aberrations found in therapy related acute myeloid leukemia (t-AML) suggest that the DNA double strand break (DSB) response may be altered. In this study we examined the DNA DSB response of primary bone marrow cells from t-AML patients and performed next-generation sequencing...
Main Authors: | Jacoby, Meagan A., de Jesus Pizarro, Rigoberto, Shao, Jin, Koboldt, Daniel, Fulton, Robert S., Zhou, Gongfu, Wilson, Richard K., Walter, Matthew J. |
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Format: | Online |
Language: | English |
Published: |
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047198/ |
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