The DNA Double-Strand Break Response Is Abnormal in Myeloblasts From Patients With Therapy-Related Acute Myeloid Leukemia

The DNA Double-Strand Break Response Is Abnormal in Myeloblasts From Patients With Therapy-Related Acute Myeloid Leukemia

The complex chromosomal aberrations found in therapy related acute myeloid leukemia (t-AML) suggest that the DNA double strand break (DSB) response may be altered. In this study we examined the DNA DSB response of primary bone marrow cells from t-AML patients and performed next-generation sequencing...

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Bibliographic Details
Main Authors: Jacoby, Meagan A., de Jesus Pizarro, Rigoberto, Shao, Jin, Koboldt, Daniel, Fulton, Robert S., Zhou, Gongfu, Wilson, Richard K., Walter, Matthew J.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047198/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047198/

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