Telomerase reverse transcriptase promoter-driven expression of iodine pump genes for targeted radioiodine therapy of malignant glioma cells

Radioiodine is a routine therapy for differentiated thyroid cancers. Non-thyroid cancers can intake radioiodine after transfection of the human sodium iodide symporter (hNIS) gene. The human telomerase reverse transcriptase (hTERT) promoter, an excellent tumor-specific promoter, has potential value...

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Bibliographic Details
Main Authors: Tan, Jian, Li, Wei, Wang, Peng
Format: Online
Language:English
Published: Sun Yat-sen University Cancer Center 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013408/