Hepatitis B virus X protein regulates the mEZH2 promoter via the E2F1-binding site in AML12 cells
Histone lysine methyltransferase EZH2 has been reported to be frequently overexpressed in hepatocellular carcinoma (HCC) tissues and associated with hepatocarcinogenesis. However, the exact mechanism of EZH2 up-regulation in HCC has not been determined. In this study, we used murine hepatocyte AML12...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Sun Yat-sen University Cancer Center
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013354/ |