Mutual regulation between CHD5 and EZH2 in hepatocellular carcinoma

Chromodomain helicase DNA binding protein 5 (CHD5) acts as a tumor suppressor in many cancers. In the present study, we demonstrated that reduced levels of CHD5 in hepatocellular carcinoma (HCC) tissues were significantly associated with metastasis and poor prognosis. Gain-of-function assays reveale...

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Bibliographic Details
Main Authors: Xie, Cheng-Rong, Li, Zhao, Sun, Hong-Guang, Wang, Fu-Qiang, Sun, Yu, Zhao, Wen-Xiu, Zhang, Sheng, Zhao, Wen-Xing, Wang, Xiao-Min, Yin, Zhen-Yu
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747380/