EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis

The accumulation of fibroblasts/myofibroblasts in fibrotic foci is one of the characteristics of idiopathic pulmonary fibrosis (IPF). Enhancer of zeste homolog 2 (EZH2) is the catalytic component of a multiprotein complex, polycomb repressive complex 2, which is involved in the trimethylation of his...

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Bibliographic Details
Main Authors: Xiao, Xiao, Senavirathna, Lakmini K., Gou, Xuxu, Huang, Chaoqun, Liang, Yurong, Liu, Lin
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027349/