Allele-Specific Genome-wide Profiling in Human Primary Erythroblasts Reveal Replication Program Organization

Allele-Specific Genome-wide Profiling in Human Primary Erythroblasts Reveal Replication Program Organization

We have developed a new approach to characterize allele-specific timing of DNA replication genome-wide in human primary basophilic erythroblasts. We show that the two chromosome homologs replicate at the same time in about 88% of the genome and that large structural variants are preferentially assoc...

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Bibliographic Details
Main Authors: Mukhopadhyay, Rituparna, Lajugie, Julien, Fourel, Nicolas, Selzer, Ari, Schizas, Michael, Bartholdy, Boris, Mar, Jessica, Lin, Chii Mei, Martin, Melvenia M., Ryan, Michael, Aladjem, Mirit I., Bouhassira, Eric E.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006724/

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