Allele-specific analysis of DNA replication origins in mammalian cells
The mechanisms that control the location and timing of firing of replication origins are poorly understood. Using a novel functional genomic approach based on the analysis of SNPs and indels in phased human genomes, we observe that replication asynchrony is associated with small cumulative variation...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479011/ |