Regulation of Wnt/β-catenin signaling by posttranslational modifications

The canonical Wnt signaling pathway (or Wnt/β-catenin pathway) plays a pivotal role in embryonic development and adult homeostasis; deregulation of the Wnt pathway contributes to the initiation and progression of human diseases including cancer. Despite its importance in human biology and disease, h...

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Bibliographic Details
Main Authors: Gao, Chenxi, Xiao, Gutian, Hu, Jing
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977945/