The Ca2+-activated K+ current of human sperm is mediated by Slo3

Sperm are equipped with a unique set of ion channels that orchestrate fertilization. In mouse sperm, the principal K+ current (IKSper) is carried by the Slo3 channel, which sets the membrane potential (Vm) in a strongly pHi-dependent manner. Here, we show that IKSper in human sperm is activated weak...

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Bibliographic Details
Main Authors: Brenker, Christoph, Zhou, Yu, Müller, Astrid, Echeverry, Fabio Andres, Trötschel, Christian, Poetsch, Ansgar, Xia, Xiao-Ming, Bönigk, Wolfgang, Lingle, Christopher J, Kaupp, U Benjamin, Strünker, Timo
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966514/