Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine

pH-regulated Slo3 channels, perhaps exclusively expressed in mammalian sperm, may play a role in alkalization-mediated K+ fluxes associated with sperm capacitation. The Slo3 channel shares extensive homology with Ca2+- and voltage-regulated BK-type Slo1 K+ channels. Here, using heterologous expressi...

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Bibliographic Details
Main Authors: Tang, Qiong-Yao, Zhang, Zhe, Xia, Xiao-Ming, Lingle, Christopher J.
Format: Online
Language:English
Published: Landes Bioscience 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723589/