A K+-selective CNG channel orchestrates Ca2+ signalling in zebrafish sperm

Calcium in the flagellum controls sperm navigation. In sperm of marine invertebrates and mammals, Ca2+ signalling has been intensely studied, whereas for fish little is known. In sea urchin sperm, a cyclic nucleotide-gated K+ channel (CNGK) mediates a cGMP-induced hyperpolarization that evokes Ca2+...

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Bibliographic Details
Main Authors: Fechner, Sylvia, Alvarez, Luis, Bönigk, Wolfgang, Müller, Astrid, Berger, Thomas K, Pascal, Rene, Trötschel, Christian, Poetsch, Ansgar, Stölting, Gabriel, Siegfried, Kellee R, Kremmer, Elisabeth, Seifert, Reinhard, Kaupp, U Benjamin
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749565/