Targeted, LCMS-based Metabolomics for Quantitative Measurement of NAD+ Metabolites

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for hydride transfer reactions and a substrate for sirtuins and other NAD+-consuming enzymes. The abundance of NAD +, NAD+ biosynthetic intermediates, and related nucleotides reflects the metabolic state of cells and tissues. High performance li...

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Bibliographic Details
Main Authors: Trammell, Samuel AJ, Brenner, Charles
Format: Online
Language:English
Published: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962138/