Methods for L-ribooligonucleotide sequence determination using LCMS
The ability to verify the sequence of a nucleic acid-based therapeutic is an essential step in the drug development process. The challenge associated with sequence identification increases with the length and nuclease resistance of the nucleic acid molecule, the latter being an important attribute o...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241672/ |