Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1

The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), either alone or in combination with other anti-cancer agents, has been considered as a new strategy for anti-cancer therapy. In this study, we demonstrated that evodiamine, a quinolone alkaloid isolated from the fruit of Evodia fru...

Full description

Bibliographic Details
Main Authors: Zhang, Tao, Qu, Shanna, Shi, Qi, He, Dalin, Jin, Xunbo
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958903/