Mithramycin A induces apoptosis by regulating the mTOR/Mcl-1/tBid pathway in androgen-independent prostate cancer cells
Mithramycin A (Mith) is an aureolic acid-type polyketide produced by various soil bacteria of the genus Streptomyces. Mith inhibits myeloid cell leukemia-1 (Mcl-1) to induce apoptosis in prostate cancer, but the molecular mechanism underlying this process has not been fully elucidated. The aim of th...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
the Society for Free Radical Research Japan
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774928/ |