NBN Phosphorylation regulates the accumulation of MRN and ATM at sites of DNA Double-Strand Breaks
In response to ionizing radiation, the MRE11/RAD50/NBN (MRN) complex re-distributes to the sites of DNA double strand breaks (DSBs) where each of its individual components is phosphorylated by the serine-threonine kinase, ATM. ATM phosphorylation of NBN is required for activation of the S-phase chec...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951136/ |