Role of Insulin Resistance in the Pathogenesis and Development of Type 2
Diabetes in WBN/Kob-Leprfa
Rats

Role of Insulin Resistance in the Pathogenesis and Development of Type 2 Diabetes in WBN/Kob-Leprfa Rats

WBN/Kob-Leprfa (fa/fa) rats have been identified as a new animal model of type 2 diabetes (T2DM), as they are characterized by impaired pancreatic insulin secretion and severe insulin resistance. Our previous study demonstrated impaired insulin secretion and its involvement in hyperglycemia in fa/fa...

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Bibliographic Details
Main Authors:	OKUNO, Akira, KAJI, Noriyuki, TAKAHASHI, Atsushi, NAGAKUBO, Dai, OHNO-ICHIKI, Kanako, SHIRAI, Mitsuyuki, ASAI, Fumitoshi
Format:	Online
Language:	English
Published:	The Japanese Society of Veterinary Science 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942958/

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