Role of Insulin Resistance in the Pathogenesis and Development of Type 2 Diabetes in WBN/Kob-Leprfa Rats
WBN/Kob-Leprfa (fa/fa) rats have been identified as a new animal model of type 2 diabetes (T2DM), as they are characterized by impaired pancreatic insulin secretion and severe insulin resistance. Our previous study demonstrated impaired insulin secretion and its involvement in hyperglycemia in fa/fa...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Japanese Society of Veterinary Science
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942958/ |