Pellino Proteins: Novel Players in TLR and IL-1R Signalling

Members of the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) family play important roles in immunity and inflammation. They initiate common intracellular signalling cascades leading to the activation of nuclear factor-κB (NF-κB) and other transcription factors that stimulate the expres...

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Bibliographic Details
Main Authors: Schauvliege, Reinout, Janssens, Sophie, Beyaert, Rudi
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922352/