Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila

Innate immunity mediated by Toll signalling has been extensively studied, but how Toll signalling is precisely controlled in balancing innate immune responses remains poorly understood. It was reported that the plasma membrane localization of Drosophila MyD88 is necessary for the recruitment of cyto...

Full description

Bibliographic Details
Main Authors: Ji, Shanming, Sun, Ming, Zheng, Xiudeng, Li, Lin, Sun, Liwei, Chen, Dahua, Sun, Qinmiao
Format: Online
Language:English
Published: Nature Pub. Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959197/