Quiescent and Proliferative Fibroblasts Exhibit Differential p300 HAT Activation through Control of 5-Methoxytryptophan Production
Quiescent fibroblasts possess unique genetic program and exhibit high metabolic activity distinct from proliferative fibroblasts. In response to inflammatory stimulation, quiescent fibroblasts are more active in expressing cyclooxygenase-2 and other proinflammatory genes than proliferative fibroblas...
Main Authors: | Cheng, Huei-Hsuan, Wang, Kai-Hsuan, Chu, Ling-yun, Chang, Tzu-Ching, Kuo, Cheng-Chin, Wu, Kenneth K. |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921189/ |
Similar Items
-
Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan
by: Cheng, Huei-Hsuan, et al.
Published: (2016) -
Endothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK Activation
by: Chu, Ling-Yun, et al.
Published: (2016) -
Quiescent Fibroblasts Are More Active in Mounting Robust Inflammatory Responses Than Proliferative Fibroblasts
by: Chen, Bo-Rui, et al.
Published: (2012) -
Quiescent fibroblasts are more active in mounting robust inflammatory responses than proliferative fibroblasts.
by: Bo-Rui Chen, et al. -
A Novel Protective Function of 5-Methoxytryptophan in Vascular Injury
by: Ho, Yen-Chun, et al.
Published: (2016)